LADR Wissenschaftliche Publikationen

Hier finden Sie wissenschaftliche Publikationen mit Beteiligung von Kolleg*innen aus den Laboratorien des LADR Laborverbundes.





Salm J, Salm F, Arendarski P, Kramer TS. High frequency of Enterococcus faecalis detected in urinary tract infections in male outpatients - a retrospective, multicenter analysis, Germany 2015 to 2020.  BMC Infect Dis. 2023 Nov 18;23(1):812. doi: 10.1186/s12879-023-08824-6 11/2023
Kramer TS, Soriano A, Tedeschi S et al. Should We Use Rifampicin in Periprosthetic Joint Infections Caused by Staphylococci When the Implant Has Been Exchanged? A Multicenter Observational Cohort Study Open Forum Infect Dis. 2023 Oct 6;10(10):ofad491. doi: 10.1093/ofid/ofad491 10/2023
Hubens WHG, Maié T, Schnitker M, Bocova L, Puri D, Wessiepe M, Kramer J, Rink L, Koschmieder S, Costa IG, Wagner W. Targeted DNA Methylation Analysis Facilitates Leukocyte Counts in Dried Blood Samples Clin Chem. 2023 Sep 14:hvad143. doi: 10.1093/clinchem/hvad143 09/2023
Salm J, Böhme T, Noory E, Beschorner U, Kramer TS, Westermann D, Zeller T. Arterial leg ulcers-Bacterial patterns, antimicrobial resistance and clinical characteristics, a retrospective single-centre cohort, 2012-2021 PLoS One. 2023 Aug 11;18(8):e0290103. doi: 10.1371/journal.pone.0290103 08/2023
Pahl A, Frohn C, Kramer J et al. Evaluierung des FetoGnost Kit RhD als nicht invasiven Pränataltest zur Bestimmung des fetalen RhD-Status (NIPT-RhD) Deutsches Register Klinischer Studien. DRKS00025039 06/2023
Creydt M, Flügge F, Dammann R, Schütze B, Günther UL, Fischer M. Food Fingerprinting: LC-ESI-IM-QTOF-Based Identification of Blumeatin as a New Marker Metabolite for the Detection of Origanum majorana Admixtures to O. onites/ vulgare Metabolites. 2023 May 20;13(5):673. doi: 10.3390/metabo13050673 05/2023
Teufel  A, Geier A, Sarrazin C, Schattenberg JM, Kautz A, Dorner R, Kramer J, Jedrysiak K et al. Intersektorales Management von Patienten mit unklarer Leberwerterhöhung und nichtalkoholischer Fettlebererkrankung (NAFLD) Z Gastroenterol. 2023 Feb 15. doi: 10.1055/a-1957-5671 02/2023
Petroff D, Wolffram I, Bätz O, Jedrysiak KKramer J, Berg T, Wiegand J. Confirmation of guideline-defined hepatitis C screening strategies within the ‘Check-Up35+’ examination in the primary care setting Liver Int. 2023 Jan 9. doi: 10.1111/liv.15516 01/2023
Thiessen H, Käding N, Gebel B, Borsche M, Graspeuntner S, Kirchhoff L, Ehlers M, Rahmöller J, Taube S, Kramer J, Klein C, Katalinic A, Rupp J.  Risk assessment of SARS-CoV-2 transmission in hospitality employees in a highly frequented tourist area Heliyon. 2022 Dec;8(12):e12177. doi: 10.1016/j.heliyon.2022.e1217 12/2022
Flügge F, Kerkow T, Kowalski P, Bornhoft J, Creydt M, Burkhard S, Günther UL. Qualitative and quantitative food authentication of oregano using NGS and
NMR with chemometrics
Food Control 2023. 145; 109497. 11/2022
Schütze B. Oregano im Focus –
Untersuchungen mit NGS und NMR
Der Lebensmittelbrief/ernährung aktuell, September/Oktober 2022 10/2022
Wilhelm L, Kramer J Gefahren durch Cannabis-Abusus CME 19, 55–66 (2022). 09/2022
Stelzhammer P, Weber W, Binder H, Sagel U, Aspöck C, Trautinger F The bacterial pathogen and resistance spectrum in a dermatological inpatient ward: a six-year, retrospective, epidemiological study GMS Hyg Infect Control. 2022 Sep 2;17:Doc16. doi: 10.3205/dgkh000419 09/2022
Thiemann C, Klitzke B, Martinetz P, Grüning P, Käster T. Barth E, Kramer J, Martinetz T Automated assessment of immunofixations with deep neural networks LaboratoriumsMedizin, 2022. doi: 10.1515/labmed-2022-0078 08/2022
Reuter T, Lange C, Zeyher S, Wölk B, Kramer J SARS-CoV-2-Antigenschnelltests  Präv Gesundheitsf (2022). doi: 10.1007/s11553-022-00970-0 08/2022
Salm J,Salm F, Arendarski P, Kramer TS High antimicrobial resistance in urinary tract infections in male outpatients in routine laboratory data, Germany, 2015 to 2020 Euro Surveill. 2022 Jul;27(30). doi: 10.2807/1560-7917.ES.2022.27.30.2101012. 07/2022
Diefenbacher S, Plotzki C, Schneider-Brachert W, Ambrosch A, Keller J, Niesalla H, Gaube S, Gastmeier P, Sassenrath C, Kramer TS Differences in observed and self-reported compliance with the 5 moments for hand hygiene as a function of healthcare workers' empathy. J Hosp Infect. 2022 Jul 11:S0195-6701(22)00223-7. doi: 10.1016/j.jhin.2022.07.008 07/2022
Kramer TS, Salm F, Schwab F, Geffers C, Behnke M, Gastmeier P, Piening B Reduction of antibacterial use in patients with very low birth weight on German NICUs after implementation of a mandatory surveillance system. A longitudinal study with national data from 2013 to 2019. J Infect. 2022 Jul;85(1):8-16. doi: 10.1016/j.jinf.2022.05.009 07/2022
Yusuf E, Roschka C, Esteban J, Raglio A, Tisler A, Willems P, Kramer TS The State of Microbiology Diagnostic of Prosthetic Joint Infection in Europe: An In-Depth Survey Among Clinical Microbiologists. Front Microbiol. 2022 Jun 20;13:906989. doi: 10.3389/fmicb.2022.906989 06/2022
Tillmann F-P, Figiel L, Ricken J, Still H, Korte C, Plaßmann G, Harth A, Jörres A, von Landenberg P Effect of Third and Fourth mRNA-Based Booster Vaccinations on SARS-CoV-2 Neutralizing Antibody Titer Formation, Risk Factors for Non-Response, and Outcome after SARS-CoV-2 Omicron Breakthrough Infections in Patients on Chronic Hemodialysis: A Prospective Multicenter Cohort Study J Clin Med. 2022 Jun 2;11(11):3187. doi: 10.3390/jcm11113187 06/2022
Vogl K, Ingenerf J,
Kramer J, Chantraine C, Drenkhahn C
LUMA: A Mapping Assistant for Standardizing the Units of LOINC-Coded Laboratory Tests Appl. Sci. 2022, 12(12), 5848. doi: 10.3390/app12125848 06/2022
Ricci G, Campanini EB, Nischikaku AS, Puccia R, Marques M, Bialek R, Rodrigues AM, Batista WL PbGP43 Genotyping Using Paraffin-Embedded Biopsies of Human Paracoccidioidomycosis Reveals a Genetically Distinct Lineage in the Paracoccidioides brasiliensis Complex Mycopathologia. 2022 Jun;187(2-3):157-168. doi: 10.1007/s11046-021-00608-3 06/2022
Sontag S, Bocova L, Hubens WGH, ... Kramer J, Rink L, Koschmieder S, Wagner W Toward Clinical Application of Leukocyte Counts Based on Targeted DNA Methylation Analysis Clin Chem. 2022 May 18;68(5):646-656. doi: 10.1093/clinchem/hvac006 05/2022
Lingscheid T, Lippert LJ, Hillus D, Kruis T, Thibeault C, Helbig ET, Tober-Lau P, Pfäfflin F, Müller-Redetzky H, Witzenrath M, Zoller T, Uhrig A, Opitz B, Suttorp N, Kramer TS, Sander LE, Stegemann MS, Kurth F.Infection Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study. Infection. 2022 Apr 14:1-12. doi: 10.1007/s15010-022-01796-w 04/2022
Klein C, Borsche M, Balck A, Föh B,...Kramer J, Twesten C, Sina C, Gillessen-Kaesbach G, Busch H, Ehlers M, Taube S, Rupp J, Katalinic A One-year surveillance of SARS-CoV-2 transmission of the ELISA cohort: A model for population-based monitoring of infection risk Sci Adv. 2022 Apr 15;8(15):eabm5016. doi: 10.1126/sciadv.abm5016 04/2022
Kramer J, Lange C, Bätz O, Schliffke M   >Corona‐Antikörper‐Titerbestimmung in Schleswig‐Holstein (CoAkTi‐SH) vor einer 4. Impfung in der Patientenversorgung von Personen über 75 Jahre in Pflegeheimen oder sonstigen Wohneinrichtungen   Schleswig-Holsteinisches Ärzteblatt 04/2022
Kouz K, Bergholz A,... Pichotka F, Trepte C, Schwedhelm E, Renné Th, Krause L, Nicklas JY, Saugel B Effect of intraoperative personalized goal-directed hemodynamic management on acute myocardial injury in high-risk patients having major abdominal surgery: a post-hoc secondary analysis of a randomized clinical trial J Clin Monit Comput 36, 1775–1783 (2022). doi: 10.1007/s10877-022-00826-0 02/2022
Sagel U Labordiagnostik von Candida spp. Im Stuhl und ihre schwierige Interpretation zaenmagazin 14. Jahrgang 2/2022: 22-28 06/2022 02/2022
Tillmann FP, Still H, von Landenberg P Long-term trajectories of SARS-CoV-2 neutralizing antibodies and predictive value of first dose vaccination-induced IgG-antibodies in hemodialysis patients  Int Urol Nephrol. 2022 Aug;54(8):1939-1945. doi: 10.1007/s11255-021-03076-2 12/2021
Petroff D, Bätz O, Jedrysiak K, Lüllau A, Kramer J, Möller H, Heyne R,
Jäger B, Berg T and Wiegand L
From Screening to Therapy: Anti-HCV Screening and Linkage to Care in a Network of General Practitioners and a Private Gastroenterology Practice Pathogens. 2021 Dec 2;10(12):1570. doi: 10.3390/pathogens10121570 12/2021

Ricci G, Boni Campanini E, Satie Nishikaku A, Puccia R, Marques M, Bialek R, Messias Rodrigues A, Luiz Batista W

PbGP43 Genotyping Using Paraffin-Embedded Biopsies of Human Paracoccidioidomycosis Reveals a Genetically Distinct Lineage in the Paracoccidioides brasiliensis Complex

Mycopathologia. 2022 Jun;187(2-3):157-168. doi: 10.1007/s11046-021-00608-3


Petroff D, Bätz O, Jedrysiak K, Kramer J, Berg T, Wiegand J

The Practicability of the Xpert HCV Viral Load Fingerstick Point-of-Care Assay in Primary Care Settings

Viruses. 2021 Nov 22;13(11):2327. doi: 10.3390/v13112327


Puyskens A, Krause E, Michel J, Nübling CM, Scheiblauer H, Bourquain D, Grossegesse M, Valusenko R,  Corman VM, Drosten C, Zwirglmaier K, Wölfel R, Lange C, Kramer J, Friesen J, Ignatius R, Müller M, Schmidt-Chanasit J, Emmerich P, Schaade L, Nitsche A

Establishment of a specimen panel for the decentralised technical evaluation of the sensitivity of 31 rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021


Euro Surveill. 2021 Nov;26(44):2100442. doi: 10.2807/1560-7917.ES.2021.26.44.2100442



Scheiblauer H, Filomena A, Nitsche A, Puyskens A, Corman VM, Drosten C, Zwirglmaier K, Lange C, Emmerich P, Müller M, Knauer O, Nübling CM

Comparative sensitivity evaluation for 122 CE-marked rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021

Euro Surveill. 2021 Nov;26(44):2100441. doi: 10.2807/1560-7917.ES.2021.26.44.2100441


Tillmann F-P, Figiel L, Ricksen J, Still H, Korte C, Plassmann G, von Landenberg P

Evolution of SARS-CoV-2-Neutralizing Antibodies after Two Standard Dose Vaccinations, Risk Factors for Non-Response and Effect of a Third Dose Booster Vaccination in Non-Responders on Hemodialysis: A Prospective Multi-Centre Cohort Study

J Clin Med. 2021 Oct 30;10(21):5113. doi: 10.3390/jcm10215113


Schmidt T , Schmidt C, Amling M, Kramer J, Barvencik F

Prevalence of low alkaline phosphatase
activity in laboratory assessment: Is
hypophosphatasia an underdiagnosed disease?

Orphanet J Rare Dis. 2021 Oct 28;16(1):452. doi: 10.1186/s13023-021-02084-w


Klapa S, Grefer J, Sobottka I, Kurowski V

A 56-Year-Old Woman with Chronic Hepatitis C Liver Disease and Meningitis due to Streptococcus equi subsp. Zooepidemicus

Case Rep Crit Care. 2021 Oct 1;2021:7227054. doi: 10.1155/2021/7227054


Burgmaier K, Brinker L, Erger F, ...Zerres K, ESCAPE Study group, GPN study group, Dötsch J, Schaefer F, Liebau MC, ARegPKD consortium

Refining genotype-phenotype correlations in 304 patients with autosomal recessive polycystic kidney disease and PKHD1 gene variants

Kidney Int. 2021 Sep;100(3):650-659. doi: 10.1016/j.kint.2021.04.019


Suwono B, Hammerl JA, Eckmanns T, Merle R, Eigner U, Lümen M, Lauter S, Stock R, Fenner I, Boemke E, Tenhagen B-A

Comparison of MICs in Escherichia coli isolates from human health surveillance with MICs obtained for the same isolates by broth microdilution

JAC Antimicrob Resist. 2021 Sep 21;3(3):dlab145. doi: 10.1093/jacamr/dlab145


Kramer TS, Walter J, Schröder C, Behnke M, Clausmeyer J, Reichardt C, Gastmeier P, Bunte K.BMC

Increase in consumption of alcohol-based hand rub in German acute care hospitals over a 12 year period.

BMC Infect Dis. 2021 Aug 6;21(1):766. doi: 10.1186/s12879-021-06427-7


Brinkmann A, Ulm S-L, Uddin S, Förster S, Seifert D, Oehme R, Corty M, Schaade L, Michel J, Nitsche A

AmpliCoV: Rapid Whole-Genome Sequencing Using Multiplex PCR Amplification and Real-Time Oxford Nanopore MinION Sequencing Enables Rapid Variant Identification of SARS-CoV-2

Front Microbiol. 2021 Jul 1;12:651151. doi: 10.3389/fmicb.2021.651151


Wareth G, Linde J, Hammer P, Splettstoesser WD et al. Molecular Characterization of German Acinetobacter baumannii Isolates and Multilocus Sequence Typing (MLST) Pathogens. 2021 Jun 1;10(6):690. doi: 10.3390/pathogens10060690 06/2021

Sakka SG, Matten J

Antibiotikatherapie in der Intensivmedizin

Deutscher Ärzteverlag, 4. überarbeitete Auflage ISBN 978-3-7691-3742-2


Kusejko K, Auñón Á, Jost B, Natividad B, Strahm C, Thurnheer C, Pablo-Marcos D, Slama D, Scanferla G, Uckay I, Waldmann I, Esteban J, Lora-Tamayo J, Clauss M, Fernandez-Sampedro M, Wouthuyzen-Bakker M, Ferrari MC, Gassmann N, Sendi P, Jent P, Morand PC, Vijayvargiya P, Trebše R, Patel R, Kouyos RD, Corvec S, Kramer TS, Stadelmann VA, Achermann Y

The Impact of Surgical Strategy and Rifampin on Treatment Outcome in Cutibacterium Periprosthetic Joint Infections.

Clin Infect Dis. 2021 Jun 15;72(12):e1064-e1073. doi: 10.1093/cid/ciaa1839


Zerres K, Rudnik-Schöneborn S, Holzgreve W

Do non-invasive prenatal tests promote discrimination against people with Down syndrome? What should be done?

Med. 2021 May 31;49(8):965-971. doi: 10.1515/jpm-2021-0204


Petruschke I, Salm F, Kaufmann M, Freytag A, Gensichen J, Behnke M, Kramer TS, Hanke R, Gastmeier P, Schneider S, RAI Study Group.Antimicrob

Evaluation of a multimodal intervention to promote rational antibiotic use in primary care.

Antimicrob Resist Infect Control. 2021 Apr 6;10(1):66. doi: 10.1186/s13756-021-00908-9


Woschke A, Faber M,...Sobottka I, Reiter-Owona I, Diefenbach A, Gosten-Heinrich P, Friesen J, Ignatius R, Aebischer T, Klotz C

Suitability of current typing procedures to identify epidemiologically linked human Giardia duodenalis isolates

PLoS Negl Trop Dis. 2021 Mar 25;15(3):e0009277. doi: 10.1371/journal.pntd.0009277


Lockhart SR, Bialek R, Kibbler CC, Cuenca-Estrella M, Jensen HE, Kontoyiannis DP

Molecular Techniques for Genus and Species Determination of Fungi From Fresh and Paraffin-Embedded Formalin-Fixed Tissue in the Revised EORTC/MSGERC Definitions of Invasive Fungal Infection

Clin Infect Dis. 2021 Mar 12;72(Suppl 2):S109-S113. doi: 10.1093/cid/ciaa1836


Petroff D, Bätz O, Jedrysiak K, Kramer J, Berg T, Wiegand J

Age dependence of liver enzymes: an analysis of over 1,300,000 consecutive blood samples

Clin Gastroenterol Hepatol. 2022 Mar;20(3):641-650. doi: 10.1016/j.cgh.2021.01.039


Cosan AS, Schweiger JU, Kahl KG, Hamann B, Deuschle M, Schweiger U, Westermair AL

Fat compartments in patients with depression: A meta-analysis

Brain Behav. 2021 Jan;11(1):e01912. doi: 10.1002/brb3.1912


Tsuprykov O, Elitok S, Buse C, Chu C, Krämer BK, Hocher B Opposite correlation of 25-hydroxy-vitamin D- and 1,25-dihydroxy-vitamin D-metabolites with gestational age, bone- and lipid-biomarkers in pregnant women Sci Rep. 2021 Jan 21;11(1):1923. doi: 10.1038/s41598-021-81452-9 01/2021

Cordes AK, Rehrauer WM, Accola MA, Wölk B, Hilfrich B, Heim A

Fully automated detection and differentiation of pandemic and endemic coronaviruses (NL63, 229E, HKU1, OC43 and SARS-CoV-2) on the Hologic Panther Fusion

J Med Virol. 2021 Jul;93(7):4438-4445. doi: 10.1002/jmv.26749


Achermann Y, Kramer TS et al.

The impact of surgical strategy and rifampin on treatment outcome in Cutibacterium periprosthetic joint infections

Clin Infect Dis. 2021 Jun 15;72(12):e1064-e1073. doi: 10.1093/cid/ciaa1839


Becker K, Radojn F, Tobisch S, Jansen V et al.

Thirty years of VRE in Germany - "expect the unexpected": The view from the National Reference Centre for Staphylococci and Enterococci

Drug Resist Updat. 2020 Dec;53:100732. doi: 10.1016/j.drup.2020.100732


Kramer TS, Bunte K, Schröder C, Behnke M, Clausmeyer J, Reichardt C, Gastmeier P, Walter J

No increase in compliance before aseptic procedures in German hospitals. A longitudinal study with data from the national surveillance system over four years.

J Hosp Infect. 2020 Sep; 106(1):71-75. doi: 10.1016/j.jhin.2020.07.001


Wandhoff B, Schröder C, Nöth U, Krause R, Schmidt B, David S, Scheller E-E, Jahn F, Behnke M, Gastmeier P, Kramer TS

Efficacy of universal preoperative decolonization with Polyhexanide in primary joint arthroplasty on surgical site infections. A multicenter before-and after-study

Antimicrob Resist Infect Control. 2020 Nov 30;9(1):188. doi: 10.1186/s13756-020-00852-0


Meyer R, Begemann M, Demuth S,...Zerres K, Kurth I, Eggermann T, Elbracht M

Inherited cases of CNOT3-associated intellectual developmental disorder with speech delay, autism, and dysmorphic facies

Clin Genet. 2020 Oct;98(4):408-412. doi: 10.1111/cge.13819


Schmidtke J, Tepplen J, Glaubitz R, Grimm, T Nippert RP, Tönnies H, Zerres K, Nippert I

Humangenetische Beratung in Deutschland: Entwicklung der Inanspruchnahme

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Sep;63(9):1161-1167. 


Wolfgang C, Wölk B, et al

Clinical characteristics of SARS-CoV-2 infection in a rural area in Germany

Rural Remote Health. 2020 Sep;20(3):6325. doi: 10.22605/RRH6325


Donnelly JP,...Bialek R et al.

Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium

Clin Infect Dis. 2020 Sep 12;71(6):1367-1376. doi: 10.1093/cid/ciz1008


Wareth G, Linde J, Hammer P, Nguyen NH, Nguyen TNM, Splettstoesser WD et al.

Phenotypic and WGS-derived antimicrobial resistance profiles of clinical and non-clinical Acinetobacter baumannii isolates from Germany and Vietnam.

Int J Antimicrob Agents. 2020 Aug 1:106127. doi:10.1016/j.ijantimicag.2020.106127


Wouthuyzen-Bakker M, Sebillotte M, Arvieux C, Fernandez-Sampedro M, Senneville E, Barbero JM, Lora-Tamayo J, Aboltins C, Trebse R, Salles MJ, Kramer TS, Ferrari, Garcia-Cañete J, Benito N, Diaz-Brito V, MD Del Toro, Scarborough M, Soriano A, ESCMID Study Group for Implant-Associated Infections (ESGIAI).

How to handle concomitant asymptomatic prosthetic joints during an episode of hematogenous PJI, a multicentre analysis.

Clin Infect Dis. 2020 Aug 18: ciaa1222. doi: 10.1093/cid/ciaa1222


Kramer TS, Bunte K, Schröder C, Behnke M, Clausmeyer J, Reichardt C, Gastmeier P, Walter J

No increase in compliance before aseptic procedures in German hospitals. A longitudinal study with data from the national surveillance system over four years.

J Hosp Infect. 2020 Sep; 106(1):71-75. doi: 10.1016/j.jhin.2020.07.001


SJS. Aghdassi, Schröder C, Lemke E, Behnke M, Fliss PM, Plotzki C, Wenk J, Gastmeier P, Kramer TS

A multimodal intervention to improve hand hygiene compliance in peripheral wards of a tertiary care university centre: a cluster randomised controlled trial.

Antimicrob Resist Infect Control. 2020 Jul 18;9(1):113. doi: 10.1186/s13756-020-00776-9


Zerres K, Arning L, Böckmann B, Purczeld A, Miterski B

Targeted Early Detection and Prevention of Hereditary Colorectal Carcinomas

Dtsch Med Wochenschr. 2020 Jul 16. doi: 10.1055/a-1154-7684


Aghdassi SJS, Gastmeier P, Behnke M, Hansen M, Kramer TS

Redundant Anaerobic Antimicrobial Prescriptions in German Acute Care Hospitals: Data from a National Point Prevalence Survey.

Antibiotics (Basel). 2020 May 28;9(6):288. doi: 10.3390/antibiotics9060288


Gröber K, Anger M, Pigulla A, Bätz O, Kramer J, Demant T, Zogbaum M

Comparative Measurements of Procalcitonin with Different Assays on Various Analytical Platforms

Clin. Lab. 2020; 66:695-698. doi: 10.7754/Clin.Lab.2019.190818


Petroff D, Bätz O, Jedrysiak K, Kramer J, Berg T, Wiegand J, Petroff D

Fibrosis-4 (FIB-4) score at the primary care level: an analysis of over 160 000 blood samples.

Gut. 2020 Apr 3:gutjnl-2020-320995. doi: 10.1136/gutjnl-2020-320995


Kramer TS, Schlosser B, Gruhl D, Behnke M, Schwab F, Gastmeier P,  Leistner R

Staphylococcus Aureus Bacteriuria as a Predictor of In-Hospital Mortality in Patients with Staphylococcus Aureus Bacteremia. Results of a Retrospective Cohort Study.

J Clin Med. 2020 Feb 13;9(2):508. doi: 10.3390/jcm9020508


Ganesan A, Wells J, Shaikh F, Peterson P, Bradley W, Carson ML, Petfield JL, Klassen-Fischer M, Akers KS, Downing K, Bialek R, Tribble DR, Wickes BL, Ganesan A

Molecular Detection of Filamentous Fungi in Formalin-Fixed Paraffin-Embedded Specimens in Invasive Fungal Wound Infections Is Feasible with High Specificity.

J Clin Microbiol. 2019 Dec 23;58(1):e01259-19. doi: 10.1128/JCM.01259-19


Kramer J, Wolffram I, Früh U, Bätz O, Berg T, Wiegand J

Laboratory reform counteracts the WHO hepatitis C elimination strategy in Germany

J Viral Hepat. 2019 Dec;26(12):1493-1495. doi: 10.1111/jvh.13188


Aghdassi SJS, Geffers C, Behnke M, Gropmann A, Gastmeier P, Kramer TS

Management of peripheral venous catheters and implementation of guidelines in Germany: a national survey.

J Hosp Infect. 2020 Jun; 105(2):311-318. doi: 10.1016/j.jhin.2019.12.023


Aghdassi SJS, Schwab F, Hansen S, Peña Diaz LA, Behnke M, Gastmeier P, Kramer TS

The quality of antimicrobial prescribing in acute care hospitals: results derived from a national point prevalence survey, Germany, 2016.

Euro Surveill. 2019 Nov; 24(46):1900281. doi: 10.2807/1560-7917.ES.2019.24.46.1900281


Kramer TS, Schwab F, Behnke M, Hansen S, Gastmeier P, Aghdassi SJS

Linezolid use in German acute care hospitals: results from two consecutive national point prevalence surveys

Antimicrob Resist Infect Control. 2019 Oct 21; 8:159. doi: 10.1186/s13756-019-0617-0. eCollection 2019


Tueffers L, Barbosa C, Bobis I, Krenz-Weinreich A et al.

Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days

Journal of Antimicrobial Chemotherapy, Volume 74, Issue 10, October 2019, Pages 2916–2925


Knies C, Olivo M, Tönnies R, von Landenberg P

Concordance of the analytical Performance of Autoimmune Antibodies on the Hob Bioclia 6500 Automated Immunoassay Analyzer to the Phadia 250 System.

ISSN No. 2456-4400, Int J Med Lab Res 2019, 4(3): 21-28


Kramer J

Vitamin D-Mangel: Hintergrund, Diagnostik und Therapie

Angewandte Komplementärmedizin AKOM. 2019; 09: 46-51


Wouthuyzen-Bakker, Kramer TS et al..

Timing of implant-removal in late acute periprosthetic joint infection: A multicenter observational study.

J Infect. 2019 Sep;79(3):199-205.doi:10.1016/j.jinf.2019.07.003


Kramer J, Wolffraum I, Früh U, Bätz O, Berg T, Wiegand J

Laboratory reform counteracts the WHO hepatitis C elimination strategy in Germany.

J Viral Hepat. 2019 Aug 6. doi: 10.1111/jvh.13188


Jansen V

Diagnosis of anemia-A synoptic overview and practical approach.

Transfus Apher Sci. 2019 Aug;58(4):375-385.doi: 10.1016/j.transci.2019.06.012


Tueffers L, Krenz-Weinreich A et al.

Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days.

J Antimicrob Chemother. 2019 Jul 17.doi:10.1093/jac/dkz297


Tsuprykov O, Buse C, Skoblo R, Hocher B Comparison of free and total 25-hydroxyvitamin D in normal human pregnancy J Steroid Biochem Mol Biol. 2019 Jun;190:29-36. doi: 10.1016/j.jsbmb.2019.03.008 06/2019
Hasan AA, von Websky K, Reichetzeder C, Tsuprykov O, Gaballa MMS, Guo J, Zeng S, Delić D, Tammen H, Klein T, Kleuser B, Hocher B Mechanisms of GLP-1 receptor-independent renoprotective effects of the dipeptidyl peptidase type 4 inhibitor linagliptin in GLP-1 receptor knockout mice with 5/6 nephrectomy Kidney Int. 2019 Jun;95(6):1373-1388. doi: 10.1016/j.kint.2019.01.010 06/2019
Zhang X, Dong Y, Sun G, Hasan AA, Tian M, Zeng S, Li J, Zeng S, Ma J, Li J, Hocher B Paternal Programming of Liver Function and Lipid Profile Induced by a Paternal Pre-Conceptional Unhealthy Diet: Potential Association with Altered Gut Microbiome Composition Kidney Blood Press Res. 2019;44(1):133-148. doi: 10.1159/000497487 03/2019

Sagel U

Resistenzstatistiken – mit Verzerrungen umgehen

Krankenhaushygiene up2date 2019; 14: 183-200 doi: 10.1055/a-0834-5409


Jansen V

Antinukleäre Antikörper Beschreibung der Fluoreszenzmuster entsprechend der neuen ICAP-Nomenklatur

arthritis + rheuma 2019; 39: 28–36 doi: 10.1055/a-0828-4338


Kramer J, Früh U

Prävention von Darmkrebserkrankungen

Präv Gesundheitsf (2019).doi: 10.1007/s11553-019-00705-8


Sakka SG, Matten J

Antibiotikatherapie in der Intensivmedizin

Deutscher Ärzteverlag, überarbeitete Auflage ISBN 978-3-7691-3655-5


Wouthuyzen-Bakker M, Kramer TS, Petersdorf S, Diaz-Brito V, Tufan ZK, Sanchez M, Arvieux C, Soriano A, ESGIAI

Clinical outcome and risk factors for failure in late acute prosthetic joint infections treated with debridement and implant retention

J Infect. 2019 Jan;78(1):40-47. doi: 10.1016/j.jinf.2018.07.014


Sunderkötter C,  Aebischer A, Bialek R et al.

Zunahme von Skabies in Deutschland und Entwicklung resistenter Krätzemilben? Evidenz und Konsequenz

Journal of the German Society of Dermatology (2019) 15-24 doi:10.1111/ddg.13706_g


Frohn C

Die gesteuerte Rhesusprophylaxe – Modifizierung eines der erfolgreichsten Verfahrens der modernen Medizin

Praktische Gynäkologie  (Fachartikel)


Frohn C

Die gezielte Rhesusprophylaxe – Spritze nur, wenn nötig

Management & Krankenhaus


Kramer T, Gastmeier P, Remschmidt C

Prosthetic joint infections.

Lancet Infect Dis. 2018 Dec;18(12):1308. doi: 10.1016/S1473-3099(18)30670-4


Du C, Mark D, Wappenschmidt B, Böckmann B et al.

A tandem duplication of BRCA1 exons 1-19 through DHX8 exon 2 in four families with hereditary breast and ovarian cancer syndrome

Breast Cancer Res Treat. 2018 Dec;172(3):561-569. doi: 10.1007/s10549-018-4957-x


He J, Lu YP, Li J, Li TY, Chen X, Liang XJ, Chen WJ, Pi SN, Hocher B, Chen YP Fetal But Not Maternal Angiotensin Converting Enzyme (ACE)-2 Gene Rs2074192 Polymorphism is Associated with Increased Risk of Being a Small For Gestational Age (SGA) Newborn Kidney Blood Press Res. 2018;43(5):1596-1606. doi: 10.1159/000494449 11/2018

Kramer T

Laborautomation kann Versorgungsqualität steigern

Management & Krankenhaus


Hocher B, Hocher CF Epigenetics of recurrent pregnancy loss EBioMedicine. 2018 Sep;35:18-19. doi: 10.1016/j.ebiom.2018.08.046 08/2018

Salzer HJF, Kuempers C, Pasternack H, Heyckendorf J, Bialek R, Palade E, Hundack L, Kalsdorf B, Lange C

An Unexpected Endobronchial Mass Appearing During Bronchoscopy

Chest. 2018 Jul;154(1):e13-e21. doi: 10.1016/j.chest.2018.03.043


Klingeberg A, Noll I, Willrich N, Feig M, Emrich D, Zill E, Krenz-Weinreich A, Kalka-Moll W, Oberdorfer K, Schmiemann G, Eckmanns T

Antibiotic-Resistant E. coli in Uncomplicated Community-Acquired Urinary Tract Infection

Dtsch Arztebl Int. 2018 Jul 23;115(29-30):494-500. doi: 10.3238/arztebl.2018.0494


Schweiger JU, Schweiger U, Hüppe M, Kahl KG, Greggersen W, Jauch-Chara K, Fassbinder E

The Use of Antidepressive Agents and Bone Mineral Density in Women: A Meta-Analysis

Int J Environ Res Public Health. 2018 Jun 30;15(7):1373. doi: 10.3390/ijerph15071373


Meier M, Kramer J, Jabs WJ, Nolte C, Hofmann J, Krüger DG, Lehnert H, Nitschke M

Proteinuria and the Clinical Course of Dobrava-Belgrade Hantavirus Infection

Nephron Extra. 2018 Feb 9;8(1):1-10. doi: 10.1159/000486322


Lüllau A, Petroff D, Bätz O, Kramer J, Jedrysiak K, Tenckhoff H, Berg T, Wolffram I, Wiegand J

Linkage to care of HbsAg-positive and anti-HCV-positive patients after a systematic screening approach in the German primary care setting.

Eur J Gastroenterol Hepatol. 2018 Mar;30(3):280-283. doi: 10.1097/MEG.0000000000001052.


Laue C, Papazova E, Liesegang A, Pannenbeckers A, Arendarski P et al.

Effect of a yoghurt drink containing Lactobacillus strains on bacterial vaginosis in women - a double-blind, randomised, controlled clinical pilot trial

Benef Microbes. 2018 Jan 29;9(1):35-50. doi: 10.3920/BM2017.0018


Frohn C

Erhebliche Diskrepanzen zwischen qualitativen Troponin-Schnelltesten („Karten-Testen“) und klassischer Laboranalytik: ist der Einsatz solcher Schnellteste vertretbar?

J Lab Med 2017; 41(4): 183–186


Meier M, Fricke L, Eikenbusch K, Smith E, Kramer J, Lehnert H, Nitschke M

The Serial Duplex Index Improves Differential Diagnosis of Acute Renal Transplant Dysfunction

J Ultrasound Med. 2017 Aug;36(8):1607-1615. doi: 10.7863/ultra.16.07032


Vogt N, Heß K, Bialek R et al.

Epileptic seizures and rhinocerebral mucormycosis during blinatumomab treatment in a patient with biphenotypic acute leukemia

Ann Hematol. 2017 Jan;96(1):151-153. doi: 10.1007/s00277-016-2837-1


Cakiroglu F, Osbahr JW, Kramer J, Rohwedel J

Differences of cell surface marker expression between bone marrow- and kidney-derived murine mesenchymal stromal cells and fibroblasts

Cell Mol Biol (Noisy-le-grand). 2016 Oct 31;62(12):11-17. doi: 10.14715/cmb/2016.62.12.3


Kaase M, Schimanski S, Schiller R, Beyreiß B, Thürmer A, Steinmann J, Kempf VA, Hess Ch, Sobottka I et al.

Multicentre investigation of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in German hospitals

IInt J Med Microbiol. 2016 Sep;306(6):415-20. doi: 10.1016/j.ijmm.2016.05.009


Zimmerli S, Bialek R, Blau IW, Christe A, Lass-Flörl C, Presterl E

Lichtheimia Infection in a Lymphoma Patient: Case Report and a Brief Review of the Available Diagnostic Tools

Mycopathologia. 2016 Aug;181(7-8):561-6. doi: 10.1007/s11046-016-0010-y


Jansen G, Mahrt N, Tueffers L, Barbosa C, Harjes M, Adolph G, Friedrichs A, Krenz-Weinreich A, Rosenstiel P, Schulenburg H

Association between clinical antibiotic resistance and susceptibility of Pseudomonas in the cystic fibrosis lung

Evol Med Public Health. 2016 Jun 14;2016(1):182-94. doi: 10.1093/emph/eow016


Frohn C

Neues aus der Rubrik „Was tun wir bei …?“ Wann kann ich meine Rhesus-D-negative Patientin oder meinen Rhesus-D-negativen Patienten mit D-positiven Erythrozytenkonzentraten versorgen?

Hämotherapie 27/2016:42-26


Pfaender S, Walter S, Todt D, Behrendt P, Doerrbecker J, Wölk B et al.

Assessment of cross-species transmission of hepatitis C virus-related non-primate hepacivirus in a population of humans at high risk of exposure

J Gen Virol. 2015 Sep;96(9):2636-2642. doi: 10.1099/vir.0.000208


Kriikku P, Hurme H, Wilhelm L, Rintatalo J, Hurme J, Kramer J, Ojanperä I

Sedative-hypnotics are widely abused by drivers apprehended for driving under the influence of drugs

Ther Drug Monit. 2015 Jun;37(3):339-46. doi: 10.1097/FTD.0000000000000138


Frickmann H, Loderstaedt U, Racz P, Tenner-Racz K, Eggert P, Haeupler A, Bialek R, Hagen RM

Detection of tropical fungi in formalin-fixed, paraffin-embedded tissue: still an indication for microscopy in times of sequence-based diagnosis?

Biomed Res Int. 2015;2015:938721. doi: 10.1155/2015/938721


Wolffram I, Petroff D, Bätz O, Jedrysiak K, Kramer J, Tenckhoff Ha, Berg T, Wiegand J, German Check-Up 35+ Study Group

Prevalence of elevated ALT values, HBsAg, and anti-HCV in the primary care setting and evaluation of guideline defined hepatitis risk scenarios

J Hepatol. 2015 Jun;62(6):1256-64. doi: 10.1016/j.jhep.2015.01.011


Dorn I, Klich K, Kramer J, Einhaus M, Kim JB, Kögler G, Wernet P, Schöler HR, Schlenke P, Zaehres H

Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin

Haematologica. 2015 Jan;100(1):32-41. doi: 10.3324/haematol.2014.108068


Kramer J

Vitamin-D-Substitution: immer notwendig?

Dtsch med Wochenschr 2015; 140(22): 1661-1666


Kriikku P, Wilhelm L, Rintatalo J, Hurme J, Kramer J, Ojanperä I

Pregabalin serum levels in apprehended drivers

Forensic Sci Int. 2014 Oct;243:112-6. doi: 10.1016/j.forsciint.2014.06.030


Kriikku P, Wilhelm L, Jenckel S, Rintatalo J, Hurme J, Kramer J, Jones AW, Ojanperä I

Comparison of breath-alcohol screening test results with venous blood alcohol concentration in suspected drunken drivers

Forensic Sci Int. 2014 Jun;239:57-61. doi: 10.1016/j.forsciint.2014.03.019


Stürenburg E, Kramer J, Schön G, Cachovan G, Sobottka I

Detection of significant bacteriuria by use of the iQ200 automated urine microscope

J Clin Microbiol. 2014 Aug;52(8):2855-60. doi: 10.1128/JCM.00112-14


Kramer J, Diehl A, Lehnert H

Epidemiologische Untersuchung zur Häufigkeit eines Vitamin-D-Mangels in Norddeutschland

Dtsch med Wochenschr 2014; 139(10): 470-475


Jäger T, Kramer J, Bätz O, Rübben H, von Ostau C, Szarvas T

Testosterone deficiency - an underestimated risk for men? Prevalence of hypogonadism

Urologe A. 2013 Dec;52(12):1684-9


Bialek R, Zelck UE

PCR-based diagnosis of mucormycosis in tissue samples

Pathologe. 2013 Nov;34(6):511-8. German. doi: 10.1007/s00292-013-1831-9


Kalus U, Wilkemeyer I, Pruss A, Caspari G
Validation of Serological Testing for Anti-Treponema pallidum from Postmortem Blood on the Siemens-BEP(®)-III Automatic System
Transfus Med Hemother. 2013 Dec;40(6):403-8. doi: 10.1159/000354070 10/2013